Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 12/20 | 0.63 |
| ▸ | PIM1 | P11309 | 3/20 | 0.58 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987937 | 1.00 | HPGD (0.63) | HPGDPIM1PIM2AKR1B1NPC1 | |
| SCHEMBL7998376 | 0.90 | HPGD (0.76) | HPGDPIM1PIM2CISD1PTPN1 | |
| SCHEMBL7998379 | 0.90 | HPGD (0.76) | HPGDPIM1PIM2CISD1PTPN1 | |
| SCHEMBL8003787 | 0.85 | HPGD (0.71) | HPGDPIM1PIM2CISD1PTPN1 | |
| SCHEMBL7996853 | 0.85 | HPGD (0.71) | HPGDPIM1PIM2CISD1PTPN1 | |
| SCHEMBL7996857 | 0.85 | HPGD (0.71) | HPGDPIM1PIM2CISD1PTPN1 | |
| SCHEMBL8003791 | 0.85 | HPGD (0.71) | HPGDPIM1PIM2CISD1PTPN1 | |
| SCHEMBL8000503 | 0.82 | HPGD (0.67) | HPGDPIM1PIM2CISD1PTPN1 | |
| SCHEMBL8000501 | 0.82 | HPGD (0.67) | HPGDPIM1PIM2CISD1PTPN1 | |
| SCHEMBL7987799 | 0.82 | HPGD (0.57) | HPGDPIM1PIM2CISD1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288096-B1 | ANTIDIABETIC AGENTS, HYPOTENSIVE AGENTS, AND ANTICHOLESTEROL AGENTS | ASTRAZENECA AB (SE) | 2001-09-11 | — | — | US | disclosed |