Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 13/20 | 0.62 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.55 |
| ▸ | MTOR | P42345 | 3/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791563 | 0.88 | PIK3CG (0.79) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL807042 | 0.82 | PI4KA (0.74) | PI4KAPIK3CGPIK3CAMTORPIK3R1 | |
| SCHEMBL10289070 | 0.82 | PI4KA (0.80) | PI4KAPIK3CGPIK3CAMTOR | |
| SCHEMBL807468 | 0.80 | PIK3CG (0.71) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL25390498 | 0.79 | PIK3CA (0.59) | PIK3CGPIK3CAMTORPIK3CDPIK3R1 | |
| SCHEMBL30572705 | 0.79 | PIK3CA (0.59) | PIK3CGPIK3CAMTORPIK3CDPIK3R1 | |
| SCHEMBL790128 | 0.79 | PIK3CG (0.70) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL807274 | 0.79 | PIK3CG (0.70) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL807458 | 0.79 | PIK3CG (0.70) | PI4KAPIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL807112 | 0.78 | PI4KA (0.62) | PI4KAPIK3CGPIK3CAMTORPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |