Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989249 | 0.86 | MAPT (0.46) | ADORA1KDM4EMAPT | |
| SCHEMBL7989573 | 0.85 | ADORA1 (0.47) | ADORA1KDM4EMAPTESR2P2RX3 | |
| SCHEMBL7992474 | 0.84 | ADORA1 (0.46) | ADORA1KDM4EMAPTESR2P2RX3 | |
| SCHEMBL6424372 | 0.83 | ADORA1 (0.53) | ADORA1KDM4EMAPTESR2P2RX3 | |
| SCHEMBL6425010 | 0.81 | ADORA1 (0.55) | ADORA1KDM4EMAPTESR2P2RX3 | |
| SCHEMBL17377126 | 0.76 | ADORA1 (0.51) | ADORA1KDM4EMAPTESR2P2RX3 | |
| SCHEMBL7986737 | 0.74 | MAPT (0.42) | ADORA1KDM4EMAPT | |
| SCHEMBL7992597 | 0.74 | ESR2 (0.50) | ADORA1KDM4EMAPTESR2P2RX3 | |
| SCHEMBL17377058 | 0.74 | ADORA1 (0.51) | ADORA1KDM4EMAPTESR2P2RX3 | |
| SCHEMBL4091052 | 0.73 | ADORA1 (0.82) | ADORA1KDM4EMAPTESR2P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |