Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 5/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992634 | 0.95 | HCRTR2 (0.43) | HCRTR2ACEKMT2AYAP1ADORA1 | |
| SCHEMBL7974748 | 0.94 | HCRTR2 (0.46) | HCRTR2KMT2AADORA1HCRTR1HRH2 | |
| SCHEMBL7974753 | 0.94 | HCRTR2 (0.46) | HCRTR2KMT2AADORA1HCRTR1HRH2 | |
| SCHEMBL7975399 | 0.94 | ADORA1 (0.42) | HCRTR2ACEKMT2AYAP1ADORA1 | |
| SCHEMBL7992516 | 0.92 | HRH2 (0.39) | HCRTR2ACEKMT2AYAP1ADORA1 | |
| SCHEMBL7975776 | 0.89 | HCRTR2 (0.47) | HCRTR2KMT2AADORA1HCRTR1HRH2 | |
| SCHEMBL7975773 | 0.89 | HCRTR2 (0.47) | HCRTR2KMT2AADORA1HCRTR1HRH2 | |
| SCHEMBL7986751 | 0.88 | ITGB3 (0.44) | HCRTR2KMT2AADORA1HCRTR1P2RX7 | |
| SCHEMBL7986850 | 0.88 | ADORA1 (0.46) | HCRTR2KMT2AADORA1HCRTR1 | |
| SCHEMBL7986852 | 0.88 | ADORA1 (0.46) | HCRTR2KMT2AADORA1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |