Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7988346

CCOC(=O)Cc1nc2c(s1)CNCC2.O=C(O)C(F)(F)F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 2/20 0.39
PARP1 P09874 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
PKM P14618 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
PDCD1 Q15116 2/20 0.33
CD274 Q9NZQ7 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GAA P10253 1/20 0.33
POLB P06746 1/20 0.33
UHRF1 Q96T88 1/20 0.33
USP2 O75604 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TRPM8 Q7Z2W7 1/20 0.32
HDAC2 Q92769 1/20 0.32
CDC7 O00311 1/20 0.31
DBF4 Q9UBU7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL31173231 0.89 UHRF1 (0.35) ADORA1HTTPDCD1CD274NPSR1
Trifluoroacetic Acid SCHEMBL17965606 0.75 PDCD1 (0.38) ADORA1SMN1; SMN2PKMHTTPDCD1
Trifluoroacetic Acid SCHEMBL207985 0.74 HDAC2 (0.38) PDCD1CD274UHRF1HDAC2FGFR3
Trifluoroacetic Acid SCHEMBL31143352 0.73 HDAC2 (0.42) ADORA1MAPTHTTGAAPOLB
Trifluoroacetic Acid SCHEMBL31143496 0.73 HDAC2 (0.37) PDCD1CD274UHRF1HDAC2FGFR3
Trifluoroacetic Acid SCHEMBL22395793 0.72 UHRF1 (0.36) SMN1; SMN2MAPTPKMPDCD1CD274
SCHEMBL977531 0.72 ADORA1 (0.52) ADORA1PARP1SMN1; SMN2MAPTPDCD1
Trifluoroacetic Acid SCHEMBL22395815 0.71 HDAC2 (0.45) PARP1PDCD1CD274UHRF1HDAC2
Hydrochloric Acid SCHEMBL978519 0.71 ADORA1 (0.53) ADORA1PARP1MEN1MAPTKMT2A
Trifluoroacetic Acid SCHEMBL8132152 0.70 TRPM2 (0.40) ADORA1SMN1; SMN2MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed