Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 8/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794434 | 0.85 | EPHX2 (0.37) | DDR1EPHX2P2RX7METAP2 | |
| SCHEMBL794885 | 0.77 | P2RX7 (0.40) | EPHX2P2RX7 | |
| SCHEMBL13826737 | 0.77 | P2RX7 (0.35) | EPHX2P2RX7 | |
| SCHEMBL792802 | 0.76 | EPHX2 (0.39) | DDR1EPHX2P2RX7NR1H4 | |
| SCHEMBL15474197 | 0.75 | AR (0.39) | P2RX7 | |
| SCHEMBL27916489 | 0.74 | P2RX7 (0.41) | P2RX7 | |
| SCHEMBL15474203 | 0.73 | EPHX2 (0.41) | EPHX2P2RX7METAP2 | |
| SCHEMBL13730515 | 0.72 | P2RX7 (0.35) | DDR1EPHX2P2RX7 | |
| SCHEMBL18372179 | 0.72 | P2RX7 (0.34) | DDR1EPHX2P2RX7 | |
| SCHEMBL13826940 | 0.71 | P2RX7 (0.33) | DDR1EPHX2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616437-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |