Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991724 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7985637 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2ADORA2ACYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7987616 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2ADORA2ACYP11B1CYP11B2 | |
| SCHEMBL7988533 | 0.87 | TAAR1 (0.43) | L3MBTL1TAAR1MAOBBRD4CYP11B1 | |
| SCHEMBL7992186 | 0.87 | CYP11B1 (0.47) | SMN1; SMN2HTTTAAR1ADORA2AADORA1 | |
| SCHEMBL7984754 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7985274 | 0.84 | GAA (0.48) | TAAR1YTHDC1ADORA2AADORA1MAOB | |
| SCHEMBL7987673 | 0.83 | YTHDC1 (0.47) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7987804 | 0.83 | YTHDC1 (0.46) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7985319 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2ADORA2ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |