Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997924 | 0.95 | AR (0.40) | GPR84KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8004476 | 0.83 | PARP1 (0.43) | GPR84KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8001404 | 0.80 | AR (0.45) | KDM4EALDH1A1HSD17B10HPGDAR | |
| SCHEMBL8004414 | 0.80 | PARP1 (0.48) | SERPINE1 | |
| SCHEMBL7989113 | 0.78 | ALDH1A1 (0.47) | GPR84KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8004454 | 0.78 | PARP1 (0.46) | GPR84KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL8001638 | 0.77 | LSS (0.41) | KDM4EALDH1A1HSD17B10HPGDGPR17 | |
| SCHEMBL8001643 | 0.77 | LSS (0.41) | KDM4EALDH1A1HSD17B10HPGDGPR17 | |
| SCHEMBL8004925 | 0.77 | ALDH1A1 (0.48) | GPR84KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7998933 | 0.77 | AR (0.38) | KDM4EALDH1A1HSD17B10HPGDAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |