Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794431 | 0.86 | EPHX2 (0.42) | EPHX2NOTUMAR | |
| SCHEMBL794714 | 0.80 | EPHX2 (0.42) | EPHX2AR | |
| SCHEMBL807896 | 0.80 | EPHX2 (0.42) | EPHX2AR | |
| SCHEMBL15465905 | 0.78 | EPHX2 (0.42) | EPHX2NOTUMAR | |
| SCHEMBL798235 | 0.77 | EPHX2 (0.45) | EPHX2NOTUMAR | |
| SCHEMBL797804 | 0.74 | EPHX2 (0.44) | EPHX2NOTUMAR | |
| SCHEMBL17874616 | 0.72 | EPHX2 (0.42) | EPHX2CYP2D6PKMCYP2C19AR | |
| SCHEMBL17874615 | 0.72 | EPHX2 (0.45) | EPHX2AR | |
| SCHEMBL17874614 | 0.71 | DDR1 (0.38) | EPHX2 | |
| SCHEMBL15467187 | 0.71 | EPHX2 (0.45) | EPHX2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616437-A1 | PESTICIDAL ARYLPYRROLIDINES | Bayer Intellectual Property GmbH (DE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |