Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 15/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798235 | 0.92 | EPHX2 (0.45) | EPHX2NOTUMCYP2C9KCNH2MCHR1 | |
| SCHEMBL794397 | 0.92 | KCNH2 (0.44) | EPHX2KCNH2MCHR1 | |
| SCHEMBL15467187 | 0.91 | EPHX2 (0.45) | EPHX2CYP2C9KCNH2MCHR1AR | |
| SCHEMBL18229242 | 0.90 | AR (0.42) | EPHX2KCNH2MCHR1AR | |
| SCHEMBL18227011 | 0.90 | AR (0.42) | EPHX2KCNH2MCHR1AR | |
| SCHEMBL794609 | 0.90 | EPHX2 (0.40) | EPHX2NOTUMKCNH2MCHR1 | |
| SCHEMBL12467240 | 0.89 | FAAH (0.40) | EPHX2NOTUM | |
| SCHEMBL792802 | 0.89 | EPHX2 (0.39) | EPHX2NOTUM | |
| SCHEMBL15467164 | 0.89 | EPHX2 (0.40) | EPHX2NOTUM | |
| SCHEMBL15466705 | 0.87 | KCNH2 (0.48) | EPHX2KCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| CN-103282347-B | Pesticidal arylpyrrolidines | BAYER IP GMBH | 2015-04-01 | — | — | CN | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | EPHX2 1332/4885NOTUM 311/4885CYP2C9 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.