Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28162024 | 0.82 | ESR2 (0.44) | NR1H2ESR2ADORA1ACHEMAPT | |
| SCHEMBL15898449 | 0.82 | ESR2 (0.44) | NR1H2ESR2ADORA1ACHEMAPT | |
| SCHEMBL15459812 | 0.78 | ESR2 (0.45) | NR1H2ESR2ADORA1ACHEMAPT | |
| SCHEMBL25275525 | 0.78 | ESR2 (0.47) | NR1H2ESR2ADORA1ACHEMAPT | |
| SCHEMBL6573257 | 0.78 | ESR2 (0.47) | NR1H2ESR2ADORA1ACHEMAPT | |
| SCHEMBL15459811 | 0.78 | ESR2 (0.47) | NR1H2ESR2ADORA1ACHEMAPT | |
| SCHEMBL6573258 | 0.78 | ESR2 (0.47) | NR1H2ESR2ADORA1ACHEMAPT | |
| SCHEMBL785942 | 0.75 | ESR2 (0.44) | NR1H2ESR2ADORA1ACHEMAPT | |
| SCHEMBL785941 | 0.75 | ESR2 (0.44) | NR1H2ESR2ADORA1ACHEMAPT | |
| SCHEMBL803643 | 0.75 | ESR2 (0.44) | NR1H2ESR2ADORA1ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |