SCHEMBL7989264

SCHEMBL7989264

CCCCCCCCOc1c(O)c2ccc(NC(=O)/C=C/c3ccc(OC(C)=O)c(OC)c3)cc2n(C)c1=O

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCHE P06276 19/20 0.46
ACHE P22303 19/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7989268 1.00 BCHE (0.46) BCHEACHE
SCHEMBL8000674 0.92 HTT (0.44) BCHEACHE
SCHEMBL8000672 0.92 HTT (0.44) BCHEACHE
SCHEMBL8000971 0.92 HTT (0.44) BCHEACHE
SCHEMBL8000967 0.92 HTT (0.44) BCHEACHE
SCHEMBL8001689 0.91 KDM1A (0.51) BCHEACHE
SCHEMBL8001693 0.91 KDM1A (0.51) BCHEACHE
SCHEMBL7997920 0.90 HTT (0.45) BCHEACHE
SCHEMBL7997918 0.90 HTT (0.45) BCHEACHE
SCHEMBL1710168 0.90 HTT (0.45) BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114352-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-09-05 US disclosed
EP-0785190-B1 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK & CHEMICALS (JP) 2000-08-16 EP disclosed
US-5942521-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-08-24 US disclosed
EP-0785190-A2 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1997-07-23 EP disclosed