Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991819 | 0.91 | MEN1 (0.52) | AURKAMEN1KMT2AMAPTGAA | |
| SCHEMBL7991779 | 0.91 | AURKA (0.49) | AURKAMEN1KMT2AMAPTGAA | |
| SCHEMBL7977876 | 0.89 | MEN1 (0.51) | AURKAMEN1KMT2AMAPTGAA | |
| SCHEMBL7989229 | 0.89 | MEN1 (0.56) | AURKAMEN1KMT2AMAPTGAA | |
| SCHEMBL7995070 | 0.89 | MEN1 (0.54) | MEN1KMT2AMAPTGAARAB9A | |
| SCHEMBL7977513 | 0.89 | MEN1 (0.54) | MEN1KMT2AMAPTGAARAB9A | |
| SCHEMBL7995572 | 0.89 | AURKA (0.47) | AURKAMEN1KMT2AMAPTGAA | |
| Hydrochloric Acid SCHEMBL7992218 | 0.89 | AURKA (0.47) | AURKAMEN1KMT2AMAPTGAA | |
| Hydrochloric Acid SCHEMBL7977943 | 0.88 | MEN1 (0.53) | MEN1KMT2AMAPTGAARAB9A | |
| SCHEMBL7977950 | 0.88 | MAPT (0.53) | MEN1KMT2AMAPTGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |