Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001550 | 0.91 | TDP1 (0.42) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL8001547 | 0.91 | TDP1 (0.42) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL8004335 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7989041 | 0.85 | TTR (0.38) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL8004883 | 0.83 | KDM4E (0.42) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL8000536 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7988407 | 0.81 | MAPT (0.36) | ALDH1A1MAPTNPSR1GAASMN1; SMN2 | |
| SCHEMBL7988679 | 0.81 | ALDH1A1 (0.40) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7998821 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KDM4EHSD17B10MAPTHPGD | |
| SCHEMBL7998548 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EHSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |