Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.35 |
| ▸ | UNG | P13051 | 3/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 5/20 | 0.31 |
| ▸ | HTR1A | P08908 | 4/20 | 0.31 |
| ▸ | HTR1D | P28221 | 4/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988791 | 0.96 | AR (0.39) | ARGPR17UNGSERPINE1ELANE | |
| SCHEMBL8001562 | 0.90 | AR (0.45) | ARGPR17UNGSERPINE1KDM4E | |
| SCHEMBL7997203 | 0.90 | AR (0.45) | ARGPR17UNGSERPINE1KDM4E | |
| SCHEMBL7998801 | 0.89 | AR (0.44) | ARGPR17UNGSERPINE1HTR1B | |
| SCHEMBL8001153 | 0.89 | AR (0.44) | ARGPR17UNGSERPINE1HTR1B | |
| SCHEMBL7988485 | 0.89 | AR (0.44) | ARGPR17UNGSERPINE1HTR1B | |
| SCHEMBL7988221 | 0.88 | AR (0.41) | ARELANEKDM4ETP53MAPT | |
| SCHEMBL8004560 | 0.85 | AR (0.47) | ARGPR17UNGSERPINE1KDM4E | |
| SCHEMBL7988426 | 0.85 | PARP1 (0.38) | GPR17HTR1BHTR1AHTR1DCNR2 | |
| SCHEMBL7998822 | 0.84 | AR (0.43) | ARGPR17UNGSERPINE1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |