Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.41 |
| ▸ | UNG | P13051 | 3/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001562 | 1.00 | AR (0.45) | ARGPR17UNGSERPINE1GPR84 | |
| SCHEMBL8001153 | 0.99 | AR (0.44) | ARGPR17UNGSERPINE1GPR84 | |
| SCHEMBL7998801 | 0.99 | AR (0.44) | ARGPR17UNGSERPINE1GPR84 | |
| SCHEMBL7988485 | 0.99 | AR (0.44) | ARGPR17UNGSERPINE1GPR84 | |
| SCHEMBL8004560 | 0.95 | AR (0.47) | ARGPR17UNGSERPINE1HSD17B10 | |
| SCHEMBL7998822 | 0.94 | AR (0.43) | ARGPR17UNGSERPINE1KDM4E | |
| SCHEMBL8000879 | 0.94 | AR (0.43) | ARGPR17UNGSERPINE1KDM4E | |
| SCHEMBL7997659 | 0.92 | GAA (0.41) | ARGPR17UNGSERPINE1KDM4E | |
| SCHEMBL7997537 | 0.90 | AR (0.38) | ARGPR17UNGSERPINE1GPR84 | |
| SCHEMBL7989467 | 0.90 | AR (0.38) | ARGPR17UNGSERPINE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |