Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991913 | 0.93 | SIRT2 (0.48) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7988436 | 0.93 | SIRT2 (0.48) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7988060 | 0.92 | SIRT2 (0.50) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7977351 | 0.89 | PDE3B (0.43) | SIRT2SIRT1SIRT3MAPTGCGR | |
| SCHEMBL7977741 | 0.89 | SIRT2 (0.48) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7988171 | 0.89 | SIRT2 (0.49) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7991299 | 0.89 | SIRT2 (0.49) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7988443 | 0.84 | PRMT5 (0.56) | SIRT2SIRT1SIRT3MAPTPTPN11 | |
| SCHEMBL7991728 | 0.82 | SIRT2 (0.53) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7990020 | 0.81 | MEN1 (0.55) | MAPTVCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |