Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991913 | 0.97 | SIRT2 (0.48) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7988436 | 0.97 | SIRT2 (0.48) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7991299 | 0.95 | SIRT2 (0.49) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7988171 | 0.95 | SIRT2 (0.49) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7989526 | 0.92 | SIRT2 (0.50) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7988623 | 0.90 | ALOX5 (0.52) | MAPTTARBP2TP53GCGRALOX5 | |
| SCHEMBL7977741 | 0.89 | SIRT2 (0.48) | SIRT2SIRT1SIRT3MAPTTARBP2 | |
| SCHEMBL7977691 | 0.87 | PRKAB2 (0.46) | MAPTTP53GCGRACHEKDM4E | |
| SCHEMBL7991891 | 0.84 | PRKAB2 (0.44) | MAPTTP53ACHEKDM4EALDH1A1 | |
| SCHEMBL7991760 | 0.84 | PRKAB2 (0.44) | MAPTTP53ACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |