Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | QDPR | P09417 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23134531 | 0.82 | CYP1A2 (0.46) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL6043112 | 0.80 | CYP1A2 (0.44) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL7974809 | 0.79 | EPHX1 (0.42) | EPHX1CYP1A2SMN1; SMN2BRD4ALDH1A1 | |
| SCHEMBL12703331 | 0.78 | EPHX2 (0.43) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL18773654 | 0.78 | EPHX2 (0.43) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL17320473 | 0.78 | EPHX2 (0.43) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL771761 | 0.78 | EPHX2 (0.40) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL4694190 | 0.77 | EPHX2 (0.42) | EPHX2EPHX1CYP1A2TDP1KDM4E | |
| SCHEMBL7989438 | 0.76 | GAA (0.59) | TDP1KDM4ESMN1; SMN2BRD4ALDH1A1 | |
| SCHEMBL13310435 | 0.76 | EPHX2 (0.39) | EPHX2EPHX1CYP1A2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |