Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12321755 | 0.83 | EPHX1 (0.44) | EPHX1BRD4CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL7989438 | 0.81 | GAA (0.59) | BRD4L3MBTL1THRBATMGAA | |
| SCHEMBL771231 | 0.79 | BRD4 (0.40) | EPHX1BRD4CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL6609940 | 0.79 | HPGD (0.55) | EPHX1L3MBTL1USP2THRBALDH1A1 | |
| SCHEMBL7986443 | 0.79 | GPR119 (0.43) | PDE4B | |
| SCHEMBL7989633 | 0.79 | EPHX2 (0.44) | EPHX1BRD4CYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL771849 | 0.79 | BRD4 (0.44) | EPHX1BRD4CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19157739 | 0.78 | EPHX1 (0.41) | EPHX1BRD4CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL14999239 | 0.78 | EPHX1 (0.38) | EPHX1BRD4CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL10193812 | 0.77 | BRD4 (0.41) | EPHX1BRD4CHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |