7-Oxocholesteryl Acetate

7-Oxocholesteryl Acetate

SCHEMBL7989640

CC(=O)OC1CC[C@@]2(C)C(=CC(=O)[C@H]3[C@@H]4CC[C@H]([C@H](C)CCCC(C)C)[C@@]4(C)CC[C@@H]32)C1

nearest known ligand 0.77

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 1/20 0.77
NPC1L1 Q9UHC9 7/20 0.74
RORA P35398 3/20 0.74
USP2 O75604 2/20 0.74
MEN1 O00255 1/20 0.74
ALOX15 P16050 1/20 0.74
KMT2A Q03164 1/20 0.74
CDC25A P30304 1/20 0.63
GABRA1 P14867 1/20 0.59
GABRB1 P18505 1/20 0.59
GABRG2 P18507 1/20 0.59
GABRB3 P28472 1/20 0.59
GABRA5 P31644 1/20 0.59
GABRA3 P34903 1/20 0.59
GABRA2 P47869 1/20 0.59
GABRA4 P48169 1/20 0.59
POLA1 P09884 1/20 0.55
CYP46A1 Q9Y6A2 2/20 0.54
RORC P51449 3/20 0.51
GPR183 P32249 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
7-Oxocholesteryl Acetate SCHEMBL27291551 1.00 NR1H3 (0.77) NR1H3NPC1L1RORAUSP2MEN1
7-Oxocholesteryl Acetate SCHEMBL19858751 1.00 NR1H3 (0.77) NR1H3NPC1L1RORAUSP2MEN1
7-Oxocholesteryl Acetate SCHEMBL4275934 1.00 NR1H3 (0.77) NR1H3NPC1L1RORAUSP2MEN1
7-Oxocholesteryl Acetate SCHEMBL14222168 1.00 NR1H3 (0.77) NR1H3NPC1L1RORAUSP2MEN1
7-Oxocholesteryl Acetate SCHEMBL14599124 1.00 NR1H3 (0.77) NR1H3NPC1L1RORAUSP2MEN1
7-Oxocholesteryl Acetate SCHEMBL4275938 1.00 NR1H3 (0.77) NR1H3NPC1L1RORAUSP2MEN1
7-Oxocholesteryl Acetate SCHEMBL24425752 1.00 NR1H3 (0.77) NR1H3NPC1L1RORAUSP2MEN1
7-Oxocholesteryl Acetate SCHEMBL19866270 1.00 NR1H3 (0.77) NR1H3NPC1L1RORAUSP2MEN1
7-Oxocholesteryl Acetate SCHEMBL19545214 1.00 NR1H3 (0.77) NR1H3NPC1L1RORAUSP2MEN1
7-Oxocholesteryl Acetate SCHEMBL21000253 1.00 NR1H3 (0.77) NR1H3NPC1L1RORAUSP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114225964-B Immobilized N-hydroxyphthalimide resin, preparation method and application thereof, and preparation method of 7-ketocholesterol acetate 厦门金达威维生素有限公司 2024-10-18 CN claimed
CN-116082428-A Preparation method and preparation device of 7-dehydrocholesterol and vitamin D3 厦门金达威维生素有限公司 2023-05-09 CN claimed
CN-114225964-A Immobilized N-hydroxyphthalimide resin, preparation method and application thereof, and preparation method of 7-ketocholesterol acetate 厦门金达威维生素有限公司 2022-03-25 CN claimed
CN-111925406-B Preparation method and application of 7-ketocholesterol acetate 上虞新和成生物化工有限公司 2021-08-17 CN claimed
CN-111138510-B Preparation method of vitamin D3 intermediate 7-ketocholesterol acetate 浙江新和成药业有限公司 2021-03-16 CN claimed
CN-111925406-A Preparation method and application of 7-ketocholesterol acetate 上虞新和成生物化工有限公司 2020-11-13 CN claimed
CN-111138510-A Preparation method of vitamin D3 intermediate 7-ketocholesterol acetate 浙江新和成药业有限公司 2020-05-12 CN claimed
CN-120084899-A HPLC analysis method capable of simultaneously controlling two different 7-dehydrocholesterol synthesis routes 苏州恩泰新材料科技有限公司 2025-06-03 CN disclosed
CN-119490393-A Synthesis method of unsaturated ketone or aromatic ketone compound 浙江工业大学 2025-02-21 CN disclosed
CN-114225964-B Immobilized N-hydroxyphthalimide resin, preparation method and application thereof, and preparation method of 7-ketocholesterol acetate 厦门金达威维生素有限公司 2024-10-18 CN disclosed
CN-114225964-B Immobilized N-hydroxyphthalimide resin, preparation method and application thereof, and preparation method of 7-ketocholesterol acetate 厦门金达威维生素有限公司 2024-10-18 CN disclosed
CN-114225964-B Immobilized N-hydroxyphthalimide resin, preparation method and application thereof, and preparation method of 7-ketocholesterol acetate 厦门金达威维生素有限公司 2024-10-18 CN disclosed
CN-116082428-A Preparation method and preparation device of 7-dehydrocholesterol and vitamin D3 厦门金达威维生素有限公司 2023-05-09 CN disclosed
WO-1995002424-A1 LOCALIZATION AND THERAPY OF NON-PROSTATIC ENDOCRINE CANCER WITH AGENTS DIRECTED AGAINST PROSTATE SPECIFIC ANTIGEN NORDION INTERNATIONAL INC. (CA) 1995-01-26 WO disclosed
EP-0572165-A1 New 7B-substituted-4-aza-5a-cholestan-ones as 5a-reductase inhibitors MERCK & CO. INC. (US) 1993-12-01 EP disclosed
WO-1993023039-A1 SUBSTITUTED 4-AZA-5A-ANDROSTAN-ONES AS 5A-REDUCTASE INHIBITORS MERCK & CO., INC. (US) 1993-11-25 WO disclosed
WO-1993023419-A1 NEW 7β-SUBSTITUTED-4-AZA-5α-CHOLESTAN-ONES AS 5α-REDUCTASE INHIBITORS MERCK & CO., INC. (US) 1993-11-25 WO disclosed
WO-1993023376-A1 NEW PROCESS FOR PRODUCING 7β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONES MERCK & CO., INC. (US) 1993-11-25 WO disclosed
US-5237064-A Process for producing 7β-substituted-aza-5αandrostan-3-ones MERCK & CO., INC. (US) 1993-08-17 US disclosed
US-5030739-A Formation Of Hydroperoxides Using An N-Hydroxydicarboxylic Acid Imide As Catalyst HOFFMAN-LA ROCHE INC. (US) 1991-07-09 US disclosed