Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 1/20 | 0.77 |
| ▸ | NPC1L1 | Q9UHC9 | 7/20 | 0.74 |
| ▸ | RORA | P35398 | 3/20 | 0.74 |
| ▸ | USP2 | O75604 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | CDC25A | P30304 | 1/20 | 0.63 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.59 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.59 |
| ▸ | POLA1 | P09884 | 1/20 | 0.55 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.54 |
| ▸ | RORC | P51449 | 3/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 7-Oxocholesteryl Acetate SCHEMBL27291551 | 1.00 | NR1H3 (0.77) | NR1H3NPC1L1RORAUSP2MEN1 | |
| 7-Oxocholesteryl Acetate SCHEMBL4275934 | 1.00 | NR1H3 (0.77) | NR1H3NPC1L1RORAUSP2MEN1 | |
| 7-Oxocholesteryl Acetate SCHEMBL14222168 | 1.00 | NR1H3 (0.77) | NR1H3NPC1L1RORAUSP2MEN1 | |
| 7-Oxocholesteryl Acetate SCHEMBL14599124 | 1.00 | NR1H3 (0.77) | NR1H3NPC1L1RORAUSP2MEN1 | |
| 7-Oxocholesteryl Acetate SCHEMBL4275938 | 1.00 | NR1H3 (0.77) | NR1H3NPC1L1RORAUSP2MEN1 | |
| 7-Oxocholesteryl Acetate SCHEMBL24425752 | 1.00 | NR1H3 (0.77) | NR1H3NPC1L1RORAUSP2MEN1 | |
| 7-Oxocholesteryl Acetate SCHEMBL19866270 | 1.00 | NR1H3 (0.77) | NR1H3NPC1L1RORAUSP2MEN1 | |
| 7-Oxocholesteryl Acetate SCHEMBL19545214 | 1.00 | NR1H3 (0.77) | NR1H3NPC1L1RORAUSP2MEN1 | |
| 7-Oxocholesteryl Acetate SCHEMBL21000253 | 1.00 | NR1H3 (0.77) | NR1H3NPC1L1RORAUSP2MEN1 | |
| 7-Oxocholesteryl Acetate SCHEMBL7989640 | 1.00 | NR1H3 (0.77) | NR1H3NPC1L1RORAUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112745253-B | Preparation of vitamin D from stigmasterol 3 Is a new method for industrialization | 成都健腾生物技术有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-110885354-B | Preparation method of 7-ketone-cholesterol acetate | 浙江新和成股份有限公司 | 2021-04-02 | — | — | CN | claimed |
| CN-110885354-A | Preparation method of 7-ketone-cholesterol acetate | 浙江新和成股份有限公司 | 2020-03-17 | — | — | CN | claimed |
| CN-107936077-A | A kind of preparation method of 7 oxo cholesterol acetate | 浙江天新药业有限公司 | 2018-04-20 | — | — | CN | claimed |
| US-20250319190-A1 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS INC (US) | 2025-10-16 | — | — | US | disclosed |
| EP-4522646-A2 | APOE LIPOPROTEIN SYSTEMS | Kisbee Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220387-A2 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| CN-112745253-B | Preparation of vitamin D from stigmasterol 3 Is a new method for industrialization | 成都健腾生物技术有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-111925406-B | Preparation method and application of 7-ketocholesterol acetate | 上虞新和成生物化工有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-113024625-A | Preparation method of 7-ketone-cholesterol acetate | 上海创诺医药集团有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-113024625-A | Preparation method of 7-ketone-cholesterol acetate | 上海创诺医药集团有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-110885354-B | Preparation method of 7-ketone-cholesterol acetate | 浙江新和成股份有限公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-111925406-A | Preparation method and application of 7-ketocholesterol acetate | 上虞新和成生物化工有限公司 | 2020-11-13 | — | — | CN | disclosed |
| US-10729701-B2 | Compounds that are analogs of squalamine, used as antibacterial agents | VIRBAC (FR) | 2020-08-04 | — | — | US | disclosed |
| CN-110885354-A | Preparation method of 7-ketone-cholesterol acetate | 浙江新和成股份有限公司 | 2020-03-17 | — | — | CN | disclosed |
| CN-107936077-A | A kind of preparation method of 7 oxo cholesterol acetate | 浙江天新药业有限公司 | 2018-04-20 | — | — | CN | disclosed |
| US-20180042942-A1 | Compounds that are Analogs of Squalamine, Used as Antibacterial Agents | VIRBAC (FR) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250319190-A1 | APOE LIPOPROTEIN SYSTEMS | APOB, APOL1, LDLR | NR1H3 16/4885NPC1L1 14/4885RORA 2643/4885 |
| US-20180042942-A1 | Compounds that are Analogs of Squalamine, Used as Antibacterial Agents | SQLE, MTX1, SPIN1 | NR1H3 3236/4885NPC1L1 1853/4885RORA 810/4885 |
| US-10729701-B2 | Compounds that are analogs of squalamine, used as antibacterial agents | SQLE, MTX1, SPIN1 | NR1H3 3236/4885NPC1L1 1853/4885RORA 810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.