Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992733 | 0.90 | SMN1; SMN2 (0.56) | GAAPOLBSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL7989438 | 0.88 | GAA (0.59) | GAAPOLBSMN1; SMN2L3MBTL1THRB | |
| SCHEMBL14293823 | 0.81 | GAA (0.50) | GAAPOLBSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL12311386 | 0.81 | GAA (0.50) | GAAPOLBSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL7989514 | 0.80 | GAA (0.46) | GAAPOLBSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL12086316 | 0.79 | GAA (0.49) | GAAPOLBSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL14275779 | 0.79 | GAA (0.53) | GAAPOLBSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL12988860 | 0.78 | GAA (0.47) | GAAPOLBSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL11578382 | 0.78 | GAA (0.56) | GAAPOLBSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL7974809 | 0.77 | EPHX1 (0.42) | GAASMN1; SMN2L3MBTL1THRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265418-B1 | ANTICOAGULANTS | UBE INDUSTRIES, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-1020467-A1 | N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF | UBE INDUSTRIES LIMITED (JP) | 2000-07-19 | — | — | EP | disclosed |