SCHEMBL798980

SCHEMBL798980

C=CC(=O)OC(C)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.42
ALDH1A1 P00352 5/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.31
THRB P10828 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14336623 0.87 TSHR (0.36) TSHR
SCHEMBL11792791 0.83 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1262753 0.83 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9679748 0.83 TSHR (0.36) TSHR
SCHEMBL9576248 0.82 HCAR2 (0.46) HCAR2
SCHEMBL23963262 0.82 TSHR (0.38) TSHR
SCHEMBL27873908 0.82 TSHR (0.38) TSHR
SCHEMBL8378307 0.82 TSHR (0.38) TSHR
SCHEMBL1263586 0.80 TSHR (0.37) TSHR
SCHEMBL9004562 0.80 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119972483-A Surface treatment process for anti-fingerprint mobile phone rear cover 深圳市芯佳通科技有限公司 2025-05-13 CN claimed
EP-0242080-B1 COPOLYMER COMPOSITIONS PARAGON OPTICAL INC (US) 1992-12-16 EP claimed
EP-0242080-A2 Copolymer compositions PARAGON OPTICAL INC (US) 1987-10-21 EP claimed
US-4661573-A INTRAOCULAR AND CONTACT LENSES; COPOLYMER OF PERFLUROALKYL ACRYLATE, ACRYLOXYALKYLPOLYSILOXANE, ACRYLOXYALKYLSILANOL, POLYACRYLOXYALKYLPOLYSILOXANE PARAGON OPTICAL INC. (US) 1987-04-28 US claimed
CN-119972483-A Surface treatment process for anti-fingerprint mobile phone rear cover 深圳市芯佳通科技有限公司 2025-05-13 CN disclosed
WO-2024223785-A1 METHOD FOR IMPRINTING OPHTHALMIC LAMINATES AND RESIST COMPOSITION THEREFOR ESSILOR INTERNATIONAL (FR) 2024-10-31 WO disclosed
EP-4454872-A1 METHOD FOR IMPRINTING OPHTHALMIC LAMINATES AND RESIST COMPOSITION THEREFOR Essilor International (FR) 2024-10-30 EP disclosed
US-12030974-B2 Composition for forming block copolymer layer for formation of microphase-separated pattern NISSAN CHEMICAL CORPORATION (JP) 2024-07-09 US disclosed
US-20220106471-A1 POLAR GROUP-CONTAINING OLEFIN COPOLYMER JAPAN POLYETHYLENE CORPORATION (JP) 2022-04-07 US disclosed
CN-113999333-A Modified fluorosilicone acrylate resin, antifouling antibacterial coating and preparation method thereof 上海沪正实业有限公司 2022-02-01 CN disclosed
WO-2020158688-A1 POLAR-GROUP-CONTAINING OLEFIN COPOLYMER 日本ポリエチレン株式会社 2020-08-06 WO disclosed
US-10042258-B2 Composition for forming a resist upper-layer film and method for producing a semiconductor device using the composition NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2018-08-07 US disclosed
US-5923397-A INTERPENETRATING NETWORK OF CROSSLINKED ACRYLIC POLYMERS; RIGID GAS PERMEABLE CORE SECTION AND SOFT EDGE SECTION ATTACHED ANNULARLY ABOUT THE CORE SECTION; EASIER TO CLEAN, PROVID GREATER VISION ACUITY AND GREATER COMFORT BAUSCH & LOMB INCORPORATED (US) 1999-07-13 US disclosed
US-5519069-A INTERPENETRATING POLYMER NETWORK, TWO CROSSLINKERS, PRECISION CASTING PILKINGTON BARNES HIND, INC. (US) 1996-05-21 US disclosed
US-5505884-A PREPARING FIRST AND SECOND MIXTURES OF POLYMERIZABLE VINYL MONOMERS, INTERRUPTING POLYMERIZATION OF THE FIRST MIXTURE BY MIXING WITH SECOND MIXTURE TO PREPARE CASTING SOLUTION, POLYMERIZING PILKINGTON BARNES HIND INC. (US) 1996-04-09 US disclosed
EP-0345994-B1 Contact lenses and materials and methods of making same PILKINGTON BARNES HIND INC (US) 1995-08-02 EP disclosed
EP-0242080-B1 COPOLYMER COMPOSITIONS PARAGON OPTICAL INC (US) 1992-12-16 EP disclosed
US-5087392-A Controlled cast molding; interrupting polymerization of first mixture of vinyl monomers by reacting with second; heating; efficient SOLA USA, INC. (US) 1992-02-11 US disclosed
EP-0242080-A2 Copolymer compositions PARAGON OPTICAL INC (US) 1987-10-21 EP disclosed
US-4661573-A INTRAOCULAR AND CONTACT LENSES; COPOLYMER OF PERFLUROALKYL ACRYLATE, ACRYLOXYALKYLPOLYSILOXANE, ACRYLOXYALKYLSILANOL, POLYACRYLOXYALKYLPOLYSILOXANE PARAGON OPTICAL INC. (US) 1987-04-28 US disclosed