Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.57 |
| ▸ | F10 | P00742 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | LOX | P28300 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425136 | 1.00 | PRSS1 (0.57) | PRSS1F10F2LOXLOXL2 | |
| SCHEMBL7986197 | 1.00 | PRSS1 (0.57) | PRSS1F10F2LOXLOXL2 | |
| SCHEMBL7392566 | 0.99 | F10 (0.56) | PRSS1F10F2LOXLOXL2 | |
| SCHEMBL7972021 | 0.96 | F10 (0.56) | PRSS1F10F2LOXLOXL2 | |
| SCHEMBL7983619 | 0.95 | F10 (0.57) | PRSS1F10F2LOXLOXL2 | |
| SCHEMBL7972008 | 0.93 | F10 (0.62) | PRSS1F10F2LOXLOXL2 | |
| Hydrochloric Acid SCHEMBL5092926 | 0.92 | LOX (0.55) | PRSS1F10F2LOXLOXL2 | |
| SCHEMBL7420039 | 0.89 | PRSS1 (0.63) | PRSS1F10F2 | |
| SCHEMBL7427347 | 0.87 | PRMT1 (0.65) | PRSS1F10F2PRMT1PLAU | |
| SCHEMBL7989663 | 0.87 | PRMT1 (0.65) | PRSS1F10F2PRMT1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |