Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.62 |
| ▸ | LOX | P28300 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.55 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.52 |
| ▸ | C1S | P09871 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972021 | 0.96 | F10 (0.56) | F10LOXLOXL2KLKB1PRSS1 | |
| SCHEMBL7392566 | 0.94 | F10 (0.56) | F10LOXLOXL2KLKB1PRSS1 | |
| SCHEMBL7425136 | 0.93 | PRSS1 (0.57) | F10LOXLOXL2PRSS1F2 | |
| SCHEMBL7986197 | 0.93 | PRSS1 (0.57) | F10LOXLOXL2PRSS1F2 | |
| SCHEMBL7989809 | 0.93 | PRSS1 (0.57) | F10LOXLOXL2PRSS1F2 | |
| SCHEMBL7983619 | 0.93 | F10 (0.57) | F10LOXLOXL2KLKB1PRSS1 | |
| SCHEMBL7982578 | 0.92 | TMPRSS2 (0.64) | F10TMPRSS2ITGB3ITGA2BPRSS1 | |
| Hydrochloric Acid SCHEMBL5092926 | 0.90 | LOX (0.55) | F10LOXLOXL2KLKB1PRSS1 | |
| SCHEMBL7972474 | 0.89 | TMPRSS2 (0.57) | F10LOXLOXL2TMPRSS2ITGB3 | |
| SCHEMBL7419632 | 0.89 | PRSS1 (0.64) | F10TMPRSS2ITGB3ITGA2BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |