Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.85 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.85 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989947 | 1.00 | ADRB3 (0.85) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7124327 | 0.87 | ADRB1 (0.66) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7121360 | 0.87 | ADRB1 (0.66) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL6620959 | 0.85 | ADRB3 (0.86) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL6620967 | 0.85 | ADRB3 (0.86) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL6620427 | 0.83 | ADRB3 (0.77) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL6621130 | 0.81 | ADRB3 (0.77) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL6621128 | 0.81 | ADRB3 (0.77) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8559634 | 0.81 | ADRB3 (0.54) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6618875 | 0.78 | ADRB3 (0.72) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291491-B1 | TREATMENT OF TYPE II DIABETES AND OBESITY; ANTIDEPRESSANTS; DECREASE GUT MOTILITY. | MERCK & CO., INC. | 2001-09-18 | — | — | US | disclosed |