SCHEMBL7989979

SCHEMBL7989979

O=C1NCC2(CCNCC2)NC1=O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NEK2 P51955 1/20 0.36
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5611779 0.98 NEK2 (0.35) NEK2
SCHEMBL340232 0.80 NEK2 (0.38) NEK2CRBN
SCHEMBL17608855 0.70 NEK2 (0.50) NEK2CRBN
SCHEMBL23244956 0.68 NEK2 (0.48) NEK2CRBN
SCHEMBL13282119 0.67 NEK2 (0.46) NEK2CRBN
SCHEMBL9655708 0.67 CRBN (0.39) NEK2CRBN
SCHEMBL18828870 0.65 CRBN (0.47) NEK2CRBN
SCHEMBL246149 0.64 SMN1; SMN2 (0.41)
SCHEMBL2516568 0.64
SCHEMBL1557616 0.64 NEK2 (0.43) NEK2CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6288061-B1 INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS WELFIDE CORPORATION (JP) 2001-09-11 US disclosed