SCHEMBL9655708

SCHEMBL9655708

O=C1NCC2(CCNCC2)C1=O

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.39
MAPKAPK2 P49137 18/20 0.34
NEK2 P51955 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1846624 0.79 CDC7 (0.38) MAPKAPK2
SCHEMBL785588 0.76 CRBN (0.52) CRBNMAPKAPK2NEK2
Hydrochloric Acid SCHEMBL29792127 0.74 CRBN (0.50) CRBNNEK2
SCHEMBL1203798 0.70 MAPKAPK2 (0.45) MAPKAPK2
SCHEMBL18343057 0.70 OTUD7B (0.32)
SCHEMBL21238835 0.70
SCHEMBL3119994 0.69 OTUD7B (0.46) CRBNNEK2
SCHEMBL324340 0.69 OTUD7B (0.46) CRBNNEK2
SCHEMBL6249399 0.67 PARP1 (0.46) MAPKAPK2
Hydrochloric Acid SCHEMBL2637685 0.67 OTUD7B (0.44) CRBNNEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0512899-A1 Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1992-11-11 EP disclosed