Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783898 | 0.97 | CHRM3 (0.56) | CHRM3ADRB2CHRM2 | |
| SCHEMBL4421627 | 0.89 | CHRM3 (0.57) | CHRM3ADRB2CHRM2 | |
| SCHEMBL10279635 | 0.87 | CHRM3 (0.56) | CHRM3ADRB2CHRM2 | |
| Hydrochloric Acid SCHEMBL381044 | 0.84 | CHRM2 (0.55) | CHRM3ADRB2CHRM2 | |
| SCHEMBL10279213 | 0.84 | CHRM3 (0.58) | CHRM3CHRM2 | |
| SCHEMBL3537104 | 0.83 | CHRM3 (0.59) | CHRM3ADRB2 | |
| SCHEMBL799322 | 0.83 | CHRM2 (0.61) | CHRM3ADRB2CHRM2 | |
| SCHEMBL10279761 | 0.83 | CHRM2 (0.52) | CHRM3CHRM2 | |
| SCHEMBL380326 | 0.83 | CHRM3 (0.64) | CHRM3 | |
| SCHEMBL4427529 | 0.83 | CHRM3 (0.56) | CHRM3ADRB2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476253-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20120071467-A1 | AMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071467-A1 | AMIDE DERIVATIVE | CHRM3, CHRM2, TACR2 | CHRM3 1/4885ADRB2 47/4885CHRM2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.