Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 9/20 | 0.47 |
| ▸ | ACE | P12821 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7976175 | 0.95 | MAPK1 (0.46) | MAPK1SMN1; SMN2ECE1ACE | |
| Trifluoroacetic Acid SCHEMBL7990414 | 0.95 | MAPK1 (0.48) | MAPK1SMN1; SMN2ECE1ACE | |
| Hydrochloric Acid SCHEMBL7989902 | 0.91 | MAPK1 (0.49) | MAPK1SMN1; SMN2ECE1ACE | |
| Trifluoroacetic Acid SCHEMBL7990087 | 0.90 | ECE1 (0.44) | ECE1ACE | |
| Trifluoroacetic Acid SCHEMBL7986445 | 0.88 | EDNRA (0.39) | MAPK1SMN1; SMN2ECE1ACE | |
| Trifluoroacetic Acid SCHEMBL7976168 | 0.86 | ECE1 (0.43) | ECE1ACE | |
| Trifluoroacetic Acid SCHEMBL7990408 | 0.84 | ECE1 (0.45) | ECE1ACE | |
| Hydrochloric Acid SCHEMBL8811696 | 0.83 | MAPK1 (0.48) | MAPK1SMN1; SMN2ECE1 | |
| SCHEMBL7993356 | 0.83 | ECE1 (0.59) | MAPK1SMN1; SMN2ECE1ACE | |
| SCHEMBL8807806 | 0.82 | MAPK1 (0.45) | MAPK1SMN1; SMN2ECE1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0792265-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015109-A1 | ENDOTHELIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-23 | — | — | WO | disclosed |