Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992780 | 0.95 | IDO1 (0.41) | IDO1AGXTALOX5HSP90AA1AR | |
| SCHEMBL7451951 | 0.90 | PTGS1 (0.36) | IDO1AGXTALOX5HSP90AA1AR | |
| SCHEMBL7510611 | 0.90 | PTGS1 (0.36) | IDO1AGXTALOX5HSP90AA1AR | |
| SCHEMBL7989889 | 0.89 | CA1 (0.47) | HSP90AA1CA1CA2CA7CA9 | |
| SCHEMBL7509273 | 0.89 | CA1 (0.47) | HSP90AA1CA1CA2CA7CA9 | |
| SCHEMBL7989942 | 0.89 | CA1 (0.47) | HSP90AA1CA1CA2CA7CA9 | |
| SCHEMBL7451503 | 0.87 | LMNA (0.52) | PRMT5WDR77L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL7515167 | 0.87 | PLA2G1B (0.38) | ESR1IDO1AGXTALOX5HSP90AA1 | |
| SCHEMBL7508492 | 0.87 | PLA2G1B (0.38) | ESR1IDO1AGXTALOX5HSP90AA1 | |
| SCHEMBL7989918 | 0.86 | CA1 (0.50) | PRMT5WDR77CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313177-B1 | AS ANTIVIRAL AGENTS | PHARMACOR INC. (CA) | 2001-11-06 | — | — | US | disclosed |