Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985849 | 0.89 | PTGS2 (0.65) | PTGS2 | |
| SCHEMBL7972928 | 0.89 | PTGS2 (0.67) | PTGS2 | |
| SCHEMBL7985910 | 0.84 | PTGS2 (0.57) | PTGS2 | |
| SCHEMBL7984583 | 0.82 | PTGS2 (0.51) | PTGS2 | |
| SCHEMBL7989315 | 0.80 | PTGS2 (0.59) | PTGS2 | |
| SCHEMBL7983488 | 0.78 | MAPK14 (0.54) | PTGS2 | |
| SCHEMBL7989398 | 0.78 | PTGS2 (0.58) | PTGS2 | |
| SCHEMBL5715568 | 0.78 | PTGS2 (0.69) | PTGS2SMN1; SMN2POLBTSHRMAPK1 | |
| SCHEMBL7981809 | 0.78 | PTGS2 (0.77) | PTGS2 | |
| SCHEMBL7983046 | 0.78 | PTGS2 (0.60) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294568-B1 | ANTIINFLAMMATORY AGENTS AND ANTITUMOR AGENTS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENTS AND COX2 ENZYME INHIBITORS | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1048649-A1 | 5-ARYLPYRROLE DERIVATIVES | NISSIN FOOD PRODUCTS CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |