Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.53 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 7/20 | 0.42 |
| ▸ | QPCT | Q16769 | 6/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986701 | 0.94 | KDR (0.53) | KDRPRKD1TDP1GSK3BQPCT | |
| SCHEMBL7988211 | 0.92 | KDR (0.53) | KDRPRKD1TDP1GSK3BQPCT | |
| SCHEMBL7990876 | 0.92 | KDR (0.56) | KDRPRKD1TDP1GSK3BQPCT | |
| SCHEMBL7993919 | 0.92 | KDR (0.58) | KDRHTR6FLT3FLT1FLT4 | |
| SCHEMBL7546697 | 0.90 | KDR (0.53) | KDRPRKD1TDP1GSK3BQPCT | |
| SCHEMBL7554248 | 0.88 | KDR (0.62) | KDRPRKD1TDP1HTR6FLT3 | |
| SCHEMBL7993991 | 0.88 | KDR (0.53) | KDRPRKD1TDP1GSK3BQPCT | |
| SCHEMBL7549158 | 0.87 | KDR (0.69) | KDRPRKD1TDP1GSK3BQPCT | |
| SCHEMBL7512866 | 0.86 | KDR (0.60) | KDRPRKD1TDP1GSK3BQPCT | |
| SCHEMBL7987165 | 0.86 | KDR (0.51) | KDRPRKD1TDP1GSK3BQPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |