Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 13/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | USP14 | P54578 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525540 | 0.87 | ALK (0.49) | BRD4CREBBPALKGSK3BMEN1 | |
| SCHEMBL7526149 | 0.81 | GSK3B (0.53) | BRD4CREBBPALKGSK3BKIT | |
| SCHEMBL7976776 | 0.73 | CDK4 (0.67) | GSK3BMEN1MAPTKMT2A | |
| SCHEMBL7987101 | 0.73 | CDK4 (0.66) | GSK3BMEN1MAPTKMT2A | |
| SCHEMBL6952413 | 0.71 | CCNE2 (0.71) | GSK3B | |
| SCHEMBL7524580 | 0.70 | GSK3B (0.58) | GSK3BMEN1MAPTKMT2A | |
| SCHEMBL7529269 | 0.70 | GSK3B (0.54) | GSK3BMEN1MAPTKMT2A | |
| SCHEMBL7990678 | 0.69 | GSK3B (0.59) | GSK3BKDR | |
| SCHEMBL7497372 | 0.68 | GSK3B (0.58) | BRD4CREBBPGSK3B | |
| SCHEMBL7523859 | 0.68 | GSK3B (0.55) | GSK3BMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281356-B1 | ANTICANRCER AGENTS | HOFFMANN-LA ROCHE INC. | 2001-08-28 | — | — | US | disclosed |