SCHEMBL7990724 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	2/20	0.57

▸	CYP2A6	P11509	2/20	0.57

▸	CCR1	P32246	3/20	0.39

▸	CCR5	P51681	3/20	0.39

▸	CCR8	P51685	2/20	0.39

▸	UHRF1	Q96T88	2/20	0.34

▸	IL5	P05113	1/20	0.34

▸	CDK2	P24941	1/20	0.32

▸	AKT1	P31749	1/20	0.32

▸	RAB9A	P51151	1/20	0.30

▸	ABL1	P00519	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7994307	0.92	CYP1A2 (0.57)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL6845000	0.78	CYP1A2 (0.61)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL21632461	0.77	CYP1A2 (0.59)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL18266965	0.77	CYP1A2 (0.64)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL2320872	0.75	CYP1A2 (0.57)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL3065915	0.75	CYP2A6 (0.57)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL6845001	0.75	CYP2A6 (0.57)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL14391751	0.75	PDPK1 (0.57)	CDK2AKT1ABL1
SCHEMBL1563936	0.75	CYP1A2 (0.57)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL1028024	0.75	CYP2A6 (0.57)	CYP1A2CYP2A6CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009131926-A1	QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS	BRISTOL-MYERS SQUIBB COMPANY (US)	2009-10-29	—	—	WO	disclosed