SCHEMBL7994307 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	CYP1A2	P05177	2/20	0.57

▸	CYP2A6	P11509	2/20	0.57

▸	CCR1	P32246	2/20	0.39

▸	CCR5	P51681	2/20	0.39

▸	CCR8	P51685	2/20	0.39

▸	ABL1	P00519	6/20	0.35

▸	UHRF1	Q96T88	2/20	0.34

▸	IL5	P05113	1/20	0.34

▸	NPC1	O15118	3/20	0.33

▸	RAB9A	P51151	3/20	0.33

▸	CASP3	P42574	1/20	0.33

▸	SENP7	Q9BQF6	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7990724	0.92	CYP1A2 (0.57)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL18266963	0.79	CYP1A2 (0.67)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL8404528	0.78	CYP1A2 (0.61)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL29404737	0.78	CYP1A2 (0.61)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL12991382	0.77	CYP1A2 (0.59)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL24457846	0.75	PDPK1 (0.57)	ABL1
SCHEMBL23676624	0.75	CYP1A2 (0.57)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL18574394	0.75	CYP1A2 (0.57)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL269264	0.75	CYP2A6 (0.57)	CYP1A2CYP2A6CCR1CCR5CCR8
SCHEMBL24207389	0.75	CYP2A6 (0.57)	CYP1A2CYP2A6CCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009131926-A1	QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS	BRISTOL-MYERS SQUIBB COMPANY (US)	2009-10-29	—	—	WO	disclosed