Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991112 | 1.00 | GPR119 (0.53) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL12226278 | 0.84 | GPR119 (0.47) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL7310710 | 0.82 | GPR119 (0.53) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL7310730 | 0.82 | GPR119 (0.53) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL20015682 | 0.80 | GPR119 (0.57) | GPR119KDM4EPKMSTSMEN1 | |
| SCHEMBL20015272 | 0.80 | GPR119 (0.57) | GPR119KDM4EPKMSTSMEN1 | |
| SCHEMBL24621773 | 0.80 | GPR119 (0.60) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL6017427 | 0.78 | GPR119 (0.46) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL6017431 | 0.78 | GPR119 (0.46) | GPR119KDM4EPKMNPC1ALDH1A1 | |
| SCHEMBL6367327 | 0.78 | GPR119 (0.55) | GPR119KDM4EPKMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265434-B1 | ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |