Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991118 | 0.81 | MAPT (0.46) | MAPTPOLBTSHRLMNAKMT2A | |
| SCHEMBL2217397 | 0.81 | SMN1; SMN2 (0.47) | MAPTPOLBTSHRLMNAKMT2A | |
| SCHEMBL6858211 | 0.76 | ALDH1A1 (0.38) | MAPTPOLBTSHRLMNAKMT2A | |
| SCHEMBL914340 | 0.72 | MEN1 (0.53) | KMT2ARXFP1ALDH1A1CYP1A1CYP1A2 | |
| SCHEMBL19161275 | 0.71 | MAPT (0.54) | MAPTPOLBTSHRLMNAKMT2A | |
| SCHEMBL19162676 | 0.70 | MAPT (0.56) | MAPTPOLBTSHRLMNAKMT2A | |
| SCHEMBL2219360 | 0.70 | PIM1 (0.60) | MAPTALDH1A1CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL18017721 | 0.69 | MAPT (0.58) | MAPTPOLBTSHRLMNAKMT2A | |
| SCHEMBL18017712 | 0.69 | MAPT (0.58) | MAPTPOLBTSHRLMNAKMT2A | |
| SCHEMBL18017878 | 0.69 | MAPT (0.58) | MAPTPOLBTSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009139792-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2009-11-19 | — | — | WO | disclosed |