Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707244 | 0.90 | RAB9A (0.48) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL7977710 | 0.90 | RAB9A (0.52) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL7991983 | 0.88 | MAPK13 (0.50) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL7991875 | 0.88 | RAB9A (0.47) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL7994926 | 0.88 | RAB9A (0.45) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL7995180 | 0.88 | MAPK1 (0.53) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| Hydrochloric Acid SCHEMBL7991518 | 0.87 | MEN1 (0.49) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL7977588 | 0.86 | SIRT2 (0.43) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL7988277 | 0.86 | SIRT2 (0.43) | RAB9AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL7987908 | 0.85 | NPC1 (0.51) | RAB9AMEN1KMT2ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |