Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991667 | 0.93 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HPGDKMT2AACP1 | |
| SCHEMBL7985609 | 0.91 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HPGDKMT2AACP1 | |
| SCHEMBL7985332 | 0.90 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2HPGDKMT2A | |
| SCHEMBL7985787 | 0.90 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2HPGDKMT2AGRIN1 | |
| SCHEMBL7985297 | 0.89 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGDKMT2AACP1 | |
| SCHEMBL7985359 | 0.88 | GRIN1 (0.45) | ALDH1A1SMN1; SMN2HPGDKMT2AACP1 | |
| SCHEMBL7974245 | 0.88 | HPGD (0.45) | ALDH1A1SMN1; SMN2HPGDKMT2AACP1 | |
| SCHEMBL7991645 | 0.88 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2HPGDKMT2AACP1 | |
| SCHEMBL7987251 | 0.88 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2HPGDKMT2AACP1 | |
| SCHEMBL7988635 | 0.88 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2HPGDKMT2AACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |