Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978064 | 0.91 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7991914 | 0.90 | MEN1 (0.45) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7988225 | 0.88 | FGFR1 (0.54) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7988650 | 0.88 | LMNA (0.48) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7977735 | 0.88 | LMNA (0.50) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7977964 | 0.87 | LMNA (0.49) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7989458 | 0.87 | LMNA (0.48) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7977692 | 0.86 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7991552 | 0.86 | LMNA (0.43) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL7991907 | 0.85 | FGFR1 (0.52) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |