Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CEL | P19835 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627736 | 0.98 | TSHR (0.46) | TSHRCELHDAC4HDAC2HDAC8 | |
| SCHEMBL3783301 | 0.87 | CEL (0.50) | CELHDAC4HDAC2HDAC8OPRL1 | |
| SCHEMBL3792040 | 0.85 | CEL (0.48) | CELHDAC4HDAC2HDAC8MEN1 | |
| SCHEMBL24069104 | 0.82 | CEL (0.46) | TSHRCELMEN1KMT2AOPRL1 | |
| SCHEMBL126651 | 0.82 | CEL (0.46) | TSHRCELMEN1KMT2AOPRL1 | |
| SCHEMBL1053897 | 0.82 | HDAC4 (0.46) | CELHDAC4HDAC2HDAC8MEN1 | |
| SCHEMBL4959102 | 0.81 | KMT2A (0.55) | HDAC4HDAC2HDAC8MEN1KMT2A | |
| SCHEMBL4556222 | 0.81 | KMT2A (0.55) | HDAC4HDAC2HDAC8MEN1KMT2A | |
| SCHEMBL4960570 | 0.81 | KMT2A (0.55) | HDAC4HDAC2HDAC8MEN1KMT2A | |
| SCHEMBL4959489 | 0.81 | KMT2A (0.55) | HDAC4HDAC2HDAC8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961372-A2 | ORAL CARE COMPOSITIONS | JOHNSON & JOHNSON CONSUMER INC. (US) | 2016-01-06 | — | — | EP | disclosed |
| EP-2961373-A2 | ORAL CARE COMPOSITIONS | JOHNSON & JOHNSON CONSUMER INC. (US) | 2016-01-06 | — | — | EP | disclosed |
| WO-2014133746-A2 | ORAL CARE COMPOSITIONS | MCNEIL-PPC, INC. (US) | 2014-09-04 | — | — | WO | disclosed |
| WO-2014133744-A2 | ORAL CARE COMPOSITIONS | MCNEIL-PPC, INC. (US) | 2014-09-04 | — | — | WO | disclosed |
| US-6287583-B1 | Low-pH, acid-containing personal care compositions which exhibit reduced sting | THE PROCTER & GAMBLE COMPANY | 2001-09-11 | — | — | US | disclosed |