SCHEMBL7991832

SCHEMBL7991832

COc1c(C)cc(C(=O)c2cc([N+](=O)[O-])ccc2Cl)c(OC)c1OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.51
KDM4E B2RXH2 1/20 0.51
RORC P51449 5/20 0.50
KMT2A Q03164 6/20 0.48
GAA P10253 5/20 0.48
MEN1 O00255 5/20 0.48
MAPK1 P28482 4/20 0.48
HTT P42858 3/20 0.48
POLB P06746 1/20 0.48
SMN1; SMN2 Q16637 6/20 0.46
MAPT P10636 5/20 0.46
LMNA P02545 4/20 0.45
CYP3A4 P08684 2/20 0.44
PPARG P37231 2/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
PKM P14618 1/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10953243 0.81 HSD17B10 (0.62) NPSR1KDM4ERORCKMT2AGAA
SCHEMBL6589148 0.79 RORC (0.56) NPSR1KDM4ERORCKMT2AGAA
SCHEMBL6586982 0.77 RORC (0.67) NPSR1KDM4ERORCKMT2AGAA
SCHEMBL7593343 0.76 KMT2A (0.57) NPSR1KDM4ERORCKMT2AGAA
SCHEMBL10727439 0.75 MAPK1 (0.81) NPSR1KDM4ERORCKMT2AGAA
SCHEMBL1762503 0.75 KMT2A (0.61) NPSR1KDM4ERORCKMT2AGAA
SCHEMBL9383327 0.74 RORC (0.61) NPSR1KDM4ERORCKMT2AGAA
SCHEMBL422653 0.74 GAA (0.64) NPSR1KDM4ERORCKMT2AGAA
SCHEMBL11362155 0.74 MAPT (0.67) NPSR1KDM4ERORCKMT2AGAA
SCHEMBL9186557 0.73 NPSR1 (0.61) NPSR1KDM4ERORCKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010031753-A1 Process for the preparation of substituted benzophenones BASF CORPORATION (US) 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010031753-A1 Process for the preparation of substituted benzophenones CYP1A1, CYP2E1, CYP1B1 NPSR1 4247/4885KDM4E 1711/4885RORC 3845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.