⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11016362 | 0.76 | KDM4E (0.38) | — | |
| SCHEMBL7350683 | 0.74 | TSHR (0.35) | — | |
| SCHEMBL6627458 | 0.74 | SLC18A3 (0.37) | — | |
| SCHEMBL536767 | 0.72 | — | — | |
| SCHEMBL537360 | 0.72 | — | — | |
| SCHEMBL536783 | 0.72 | — | — | |
| SCHEMBL28124381 | 0.72 | KDM4E (0.30) | — | |
| SCHEMBL7647881 | 0.72 | — | — | |
| SCHEMBL25661035 | 0.70 | CYP1A2 (0.43) | — | |
| SCHEMBL7126010 | 0.70 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570645-B2 | Uses of p53 x-ray co-crystal structures | PMV PHARMACEUTICALS, INC. (US) | 2026-03-10 | — | — | US | disclosed |
| US-20260027097-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-12419880-B2 | Companion diagnostic tool for mutant p53 reactivating compounds | PMV PHARMACEUTICALS, INC. (US) | 2025-09-23 | — | — | US | disclosed |
| US-20240269126-A1 | COMBINATION THERAPY FOR TREATMENT OF CANCER | PMV PHARMACEUTICALS, INC. | 2024-08-15 | — | — | US | disclosed |
| US-11938124-B2 | Combination therapy for treatment of cancer | PMV PHARMACEUTICALS, INC. (US) | 2024-03-26 | — | — | US | disclosed |
| US-20230049952-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. | 2023-02-16 | — | — | US | disclosed |
| US-20230044826-A1 | COMPANION DIAGNOSTIC TOOL FOR MUTANT P53 REACTIVATING COMPOUNDS | PMV PHARMACEUTICALS, INC. | 2023-02-09 | — | — | US | disclosed |
| US-20230033324-A1 | COMBINATION THERAPY FOR TREATMENT OF CANCER | PMV PHARMACEUTICALS, INC. | 2023-02-02 | — | — | US | disclosed |
| US-20230024905-A1 | USES OF P53 X-RAY CO-CRYSTAL STRUCTURES | PMV PHARMACEUTICALS, INC. | 2023-01-26 | — | — | US | disclosed |
| EP-3679034-A1 | 1-(4-(ISOXAZOL-5-YL)-1H-PYRAZOL-1-YL)-2-METHYLPROPAN-2-OL DERIVATIVES AND RELATED COMPOUNDS AS IL-17 AND IFN-GAMMA INHIBITORS FOR TREATING AUTOIMMUNE DISEASES AND CHRONIC INFLAMMATION | Immunic AG (DE) | 2020-07-15 | — | — | EP | disclosed |
| EP-2711383-B1 | CATALYST SOLUTION FOR USE IN PRODUCTION OF POLYESTER, AND METHOD FOR PRODUCING POLYESTER RESIN USING SAME | TORAY INDUSTRIES (JP) | 2018-07-04 | — | — | EP | disclosed |
| CN-104059073-B | Imidazopyrizine Syk Inhibitors | 吉利德康涅狄格公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-105727828-A | Cationic gemini surfactants and preparation method thereof | 江南大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-103534291-B | Catalyst solution for use in production of polyester, and method for producing polyester resin using same | TORAY INDUSTRIES | 2015-06-24 | — | — | CN | disclosed |
| US-20150045530-A1 | CATALYST SOLUTION FOR USE IN PRODUCTION OF POLYESTER, AND METHOD FOR PRODUCING POLYESTER RESIN USING SAME | TORAY INDUSTRIES, INC. (JP) | 2015-02-12 | — | — | US | disclosed |
| EP-2711383-A1 | CATALYST SOLUTION FOR USE IN PRODUCTION OF POLYESTER, AND METHOD FOR PRODUCING POLYESTER RESIN USING SAME | Toray Industries, Inc. (JP) | 2014-03-26 | — | — | EP | disclosed |
| CN-103534291-A | Catalyst solution for use in production of polyester, and method for producing polyester resin using same | TORAY INDUSTRIES | 2014-01-22 | — | — | CN | disclosed |
| US-6291596-B1 | CONTACTING OLEFINICALLY UNSATURATED COMPOUND WITH HYDROGEN IN THE PRESENCE OF A HYDROGENATION CATALYST COMPRISING TITANIUM OR ZIRCONIUM OR HAFNIUM COMPOUND IN AN INERT, ORGANIC SOLVENT | JSR CORPORATION (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-0974602-A1 | Catalyst and process for hydrogenating olefinically unsaturated compound | JSR Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |
| US-4336061-A | Herbicidal azolyl chloroacetanilides, compositions and method of use | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-22 | — | — | US | disclosed |