Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848241 | 0.85 | GPR84 (0.41) | — | |
| SCHEMBL6627458 | 0.81 | SLC18A3 (0.37) | KDM4E | |
| SCHEMBL28123946 | 0.74 | TSHR (0.39) | — | |
| SCHEMBL7148428 | 0.73 | MAPT (0.41) | — | |
| SCHEMBL28078662 | 0.71 | KDM4E (0.32) | KDM4E | |
| SCHEMBL13810689 | 0.71 | MAPT (0.39) | KDM4E | |
| SCHEMBL13810692 | 0.71 | MAPT (0.39) | KDM4E | |
| SCHEMBL7991895 | 0.70 | — | — | |
| SCHEMBL12917715 | 0.70 | KDM4E (0.30) | KDM4E | |
| SCHEMBL11124357 | 0.69 | AOC3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806267-B1 | ANTITUMOUR AGENTS; OVERCOMING CHRONIC MYELOID LEUKEMIA ASSOCIATED DRUG RESISTANCE; SUCH AS 4-ACETOXY-5-PHENYL-NAPHTO(2,3-B)PYRROLO(1,2-D)(1,4)OXAZEPINE | THE UNIVERSITA'DI SIENA (IT) | 2004-10-19 | — | — | US | disclosed |
| EP-1255758-A1 | APOPTOSIS-INDUCING COMPOUNDS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001058904-A9 | APOPTOSIS-INDUCING COMPOUNDS | TRINITY COLLEGE DUBLIN (IE) | 2002-02-21 | — | — | WO | disclosed |
| WO-2001058904-A1 | APOPTOSIS-INDUCING COMPOUNDS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2001-08-16 | — | — | WO | disclosed |
| WO-1999056736-A2 | APOPTOSIS-INDUCING COMPOUNDS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 1999-11-11 | — | — | WO | disclosed |