SCHEMBL7991940

SCHEMBL7991940

COc1ccc(-c2nnc(C(C)(C)Oc3c(F)cc(N)cc3OC)n2C)c(C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 7/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7981724 0.87 HSD11B1 (0.40) HSD11B1
SCHEMBL7995023 0.87 EPHX2 (0.34) HSD11B1
SCHEMBL12671161 0.86 AR (0.37) HSD11B1
SCHEMBL7995022 0.85 HSD11B1 (0.45) HSD11B1
SCHEMBL12671160 0.83 HSD11B1 (0.36) HSD11B1
SCHEMBL7984863 0.80 HSD11B1 (0.40) HSD11B1
SCHEMBL7985114 0.79 HSD11B1 (0.40) HSD11B1
SCHEMBL7981340 0.78 HSD11B1 (0.43) HSD11B1
SCHEMBL7984670 0.78 HSD11B1 (0.46) HSD11B1
Hydrochloric Acid SCHEMBL1417901 0.78 HSD11B1 (0.39) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010001946-A1 TRIAZOLE DERIVATIVE OR SALT THEREOF アステラス製薬株式会社 (JP) 2010-01-07 WO disclosed