Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HK1 | P19367 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990688 | 0.96 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7991553 | 0.92 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7977815 | 0.92 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7978135 | 0.92 | ALOX5 (0.56) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7989527 | 0.91 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7978079 | 0.91 | MEN1 (0.59) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7988486 | 0.90 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7978324 | 0.89 | MEN1 (0.57) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7977354 | 0.88 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7988634 | 0.88 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | claimed |
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |