SCHEMBL7992005

SCHEMBL7992005

Cc1c(C(=O)O)ccc2c1S(=O)(=O)CCC2=O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 3/20 0.46
SLC22A6 Q4U2R8 1/20 0.35
SLC22A8 Q8TCC7 1/20 0.35
HAAO P46952 1/20 0.33
CYP1A2 P05177 1/20 0.31
TSHR P16473 1/20 0.30
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
MMP14 P50281 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
POLB P06746 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8166451 0.81 CXCR2 (0.41) CXCR2
SCHEMBL8596112 0.79 CXCR2 (0.44) CXCR2POLBCA2
SCHEMBL8134119 0.76 PTK2 (0.35) CXCR2HAAOCYP1A2DDB1CRBN
SCHEMBL7990916 0.75 KMT2A (0.36) SLC22A6SLC22A8POLB
SCHEMBL7619023 0.74 CYP1A2 (0.34) HAAOCYP1A2TSHRDDB1CRBN
SCHEMBL23446590 0.73 CXCR2 (0.51) CXCR2POLBCA2
SCHEMBL10164854 0.72 SLC22A8 (0.49) SLC22A6SLC22A8HAAOCYP1A2TSHR
SCHEMBL8133758 0.72 SPR (0.42) CXCR2KDM4E
SCHEMBL15556851 0.70 SLC22A6 (0.43) SLC22A6SLC22A8SMN1; SMN2POLB
SCHEMBL6895329 0.70 HAAO (0.35) SLC22A6SLC22A8HAAOCYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6291682-B1 FOR CONTROLLING WEEDS BASF AKTIENGESELLSCHAFT (DE) 2001-09-18 US disclosed
US-6054414-A HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 2000-04-25 US disclosed