Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988657 | 0.90 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7974255 | 0.88 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7988672 | 0.87 | SMN1; SMN2 (0.47) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 | |
| SCHEMBL7988531 | 0.87 | ALDH1A1 (0.44) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 | |
| SCHEMBL7975136 | 0.87 | HPGD (0.45) | HPGDALDH1A1SMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7985271 | 0.87 | GAA (0.51) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 | |
| SCHEMBL7985634 | 0.87 | SMN1; SMN2 (0.57) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 | |
| Hydrochloric Acid SCHEMBL7987615 | 0.85 | SMN1; SMN2 (0.56) | HPGDALDH1A1SMN1; SMN2KMT2AHCAR2 | |
| SCHEMBL7988361 | 0.85 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2KMT2ACYP11B1 | |
| SCHEMBL7992187 | 0.83 | ALDH1A1 (0.43) | HPGDALDH1A1SMN1; SMN2KMT2ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |